Sinhon thiourea | Application of thiourea in pharmaceuticals

Thiourea is a sulfur-containing organic compound with the chemical formula SC(NH₂)₂. Due to its unique chemical properties, it has many important applications in the medical field. The following are the main uses of thiourea in medicine:

1. Antithyroid drugs

Thiourea and its derivatives (such as propylthiouracil and methimazole) are commonly used drugs for the treatment of hyperthyroidism (hyperthyroidism). They inhibit thyroid peroxidase and block the synthesis of thyroid hormones, thereby relieving the symptoms of hyperthyroidism.

2. Antioxidant and cell protection

Thiourea can be used as a free radical scavenger to protect cells from oxidative damage. Studies have shown that thiourea derivatives have potential application value in anti-inflammatory, anti-aging and neuroprotection.

3. Anti-tumor research

Some thiourea derivatives show anti-tumor activity and can inhibit cancer cell proliferation or induce apoptosis. For example, thiourea compounds have shown certain anti-cancer potential in studies of breast cancer and liver cancer.

4. Antibacterial and antiviral agents

Thiourea structurally modified compounds have inhibitory effects on bacteria, fungi and viruses, and can be used to develop new antibacterial drugs or assist in the treatment of infectious diseases.

5. Drug synthesis intermediates

Thiourea is a key intermediate for the synthesis of a variety of drugs, such as sulfonamide antibiotics, anti-tuberculosis drugs, etc., and plays an important role in pharmaceutical chemistry.

In summary, thiourea and its derivatives are widely used in the medical field, from direct treatment of hyperthyroidism to potential anti-cancer and antibacterial effects, showing their diverse pharmacological activities. In the future, through structural optimization and in-depth research, thiourea compounds may provide more possibilities for the development of new drugs.

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