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What is the use of thiourea in pharma?

28-Apr-2024

What is the use of thiourea in pharma?


Thiourea, a sulfur-containing compound, has several applications in the pharmaceutical industry:


Pharmaceutical synthesis: Thiourea serves as a precursor in the synthesis of various pharmaceutical compounds, including antithyroid drugs, antibiotics, antiviral agents, and anticancer medications.


Metal chelation: It can form complexes with certain metals, which finds application in pharmaceutical formulations. These complexes may enhance drug stability or alter drug properties for better therapeutic effects.


Analytical chemistry: Thiourea is used in analytical chemistry as a reagent for detecting and quantifying certain compounds. It can form colored complexes with various substances, aiding in their identification and measurement.


Organic reactions: Thiourea catalyzes a variety of organic reactions, such as the asymmetric synthesis of chiral compounds. This property is valuable in pharmaceutical synthesis, where enantiomerically pure compounds are often required.


Antioxidant: Thiourea exhibits antioxidant properties, which may be exploited in pharmaceutical formulations to protect drugs from degradation due to oxidation, thus enhancing their stability and shelf life.


Overall, thiourea's diverse chemical properties make it a valuable component in pharmaceutical research, synthesis, and formulation.



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